Our team is interested in macrocomplexes of the bacterial enveloppe that energize essential functions in bacteria, such as cell division and transport across the membranes. We use Escherichia coli and the human pathogen Vibrio cholerae as a model organisms to explore the structure and function of two of these conserved molecular motors: the Tol-Pal and the TonB-ExbB-ExbD systèmes.
Tol-Pal, Tol and Ton molecular motor, protein-protein interactions, proton-motive force, cell division, colicins, filamentous phages, host-phage interaction
Biochemistry, Genetics, Microbiology, Microscopy, Molecular Biology
about 400 hrs/year
at Aix-Marseille University :
Biochemistry, Microbiology, Synthetic Biology, Genetics
S. Buchanan, NIDDK, NIH, Bethesda, MD, USA
T. Mignot, LCB UMR7283, Marseille, France